The active constituents are several complex sulfurcontaining compounds that are rapidly absorbed, transformed and metabolized. In vitro and clinical studies were conducted on human liver microsomes and healthy human subjects, respectively. Medicinal plants have been used from ancient times for human healthcare as in the form of traditional medicines, spices, and other food components. Allium sativum, garlic, leishmania, organosulfur compounds, allicin, ajoene received september 21, 2015. Journal of food international tfi2012, traditional foods. This study was aimed to evaluate the fungal microflora in meju samples fermented using single andor multiple additions of ethanolic extracts from plants, including nelumbo nucifera leaves, ginkgo biloba leaves, and allium sativum cloves, at different concentrations 1 and 10% and mixtures of these extracts at a 1. Research in recent decades has shown widespread pharmacological and therapeutic effects of a. Full text pdf journal of applied pharmaceutical science. Subjects architecture and design arts asian and pacific studies business and economics chemistry classical and ancient near eastern studies computer sciences cultural studies engineering general interest geosciences history industrial chemistry islamic and middle eastern studies jewish studies law library and information science, book studies life sciences linguistics and semiotics literary. Leishmaniasis is a vectorborne disease that is caused by an obli. The present study evaluated the antimicrobial activity of allium sativum extract against the biofilms of six pathogenic bacteria and their freeliving forms. Some of the earliest references to this medicinal plant were found in avesta, a collection of zoroastrian holy writings that was. Dextromethorphan was used as a common marker for measuring metabolic activity of cyp2d6 and cyp3a4 enzymes.
Ajoene, a compound derived from garlic allium sativum l. Among these, garlic allium sativum is one of the most widely used ones. Antioxidant properties of raw garlic allium sativum extract 591 international food research journal 192. Various sources of b fertilizers such as borax, coal fly ash, and fritted trace elements were applied to the soil to.
Cd 4 cells of the rats were estimated using partec flow. Phytochemical investigation of fresh, powdered and anatomical sections of fruit of coriander sativum were carried out to determine its micro morphological and physical evaluation profiles. The final product by this procedure was soft and sweet with a less irritating odor and fruity taste. Characterization of active compounds of different garlic allium sativum l. Lepidium sativum garden cress belonging to cruciferae family, widely grown in india, europe and us. Garlic allium sativum is used as a flavoring ingredient in food preparations and promoted as a ds for patients with hypertension and hyperlipidemia, and for preventing cardiovascular disease. Field experiments were conducted following rice cultivation on major soils typic tropaqualfs in the northern parts of thailand. Pharmacological basis for the medicinal use of lepidium. Garlic allium sativum is a source of medicine in many ways in human beings in routine life as well as in animals and its leaves, flowers, and cloves have been used in traditional medicine for a.
How lepidium sativum is effective for various diseases is listed in repertory format. Chiang mai has been identified at san pa tong rice experiment station, chiang mai province. It has been reported to possess several biological properties including anticarcinogenic, antioxidant. Garlic allium sativum is a source of medicine in many ways in human beings in routine life as. Antioxidant properties of raw garlic allium sativum extract. It is renowned throughout the world for its distinctive flavour as well as its healthgiving properties. Uses, benefits, cures, side effects, nutrients in lepidium sativum. For this purpose, six different extracts were prepared, using five different polar solvents methanol, ethyl acetate, petroleum ether, chloroforms and butanol and water.
Phylogeny and biogeography of allium amaryllidaceae. It can be concluded that allium tuberosum species of garlic is a more potent hypolipidemic and antiatherosclerotic agent as compared to allium sativum. Lepidium sativum description is available in the ayurvedic classical text. Effect of inorganic and biofertilizer on growth and yield of garlic allium sativum l. Simultaneous speciation of selenium and sulfur species in selenized odorless garlic allium sativum l. The powder and alcoholic extract of dried seeds of garden cress were investigated for their effect on metabolic activity of cyp2d6 and cyp3a4 enzymes. The second group was administered allium sativum powder 200 mgkg of body weight orally for 7 successive. The use of the cryogenic gcms and oncolumn injection for study of organosulfur compounds of the allium sativum. Review article leaves ofcoriandrum sativum as an indigenous. Efficacy of allium sativum garlicin controlling nematode parasites in sheep masamha. Black garlic allium sativum was produced from ordinary white garlic allium sativum clove by processing it in a temperature 70c and humidity 75%controlled room for a month. Neuroprotective potential of allium sativum against. Phytopharmacological properties of coriander sativum as a. Pdf effect of allium sativum extract on erythromycin and.
This study was aimed to evaluate the antimicrobial activity of garlicextracted samples against bacteria and fungi at different concentration, in various polar solvents. Garlic in particular, is reportedly effective against a wide range of diseasecausing pathogens and insect pests at different stages in their life cycles. It is native to central asia and northeastern iran, and has long been a common seasoning worldwide, with a history of several thousand years of human consumption and use. A previously unknown requirement for b by garlic var. Effect of garden cress seeds powder and its alcoholic extract.
The search for efficient, organic, and environmentfriendly molluscicide that could minimize the spread of the invasive golden apple snail pomacea canaliculata in the philippines is still on going. Effect of different solvent extracted sample of allium. Pdf pharmacological effects of garlic allium sativum l. The aim of the work is to standardize allium sativum by formulating them into tablets dosage. Chemical composition and bioactive compounds of garlic allium sativum l. Classification of genetic variation in garlic allium sativum l.
Effect of inorganic and organic fertilizers on the growth and yield of garlic crop allium sativum l. Nourishing and healing prowess of garden cress lepidium. Efficacy of allium sativum garlicin controlling nematode. Effect of garlic allium sativum on blood lipids, blood sugar, fibrinogen and. Effect of boron sources on garlic allium sativum l. Pisum sativum, commonly known as pea, is a valuable food source for millions of people throughout the world.
The mode of action of aqueous garlic extract age was studied in candida albicans. In this study, antimicrobial activities of two different samples of allium sativum l. In addition to the wild garlic, the so called field garlic in europe and north america does also occur to refer to allium vineale. The minimum inhibitory concentration mic of age against six clinical yeast isolates ranged between 0. Garlic has played important dietary and medicinal roles throughout the history. Characterization of active compounds of different garlic allium. A broad spectrum of gramnegative and grampositive bacteria 17 bacteria including species of bacillus, enterobacter, enterococcus, escherichia, klebsiella, listeria, pseudomonas, salmonella, and staphylococcus were. The clinical isolates in this study had not been studied in any other studies, especially in regard to biofilm disruption and inhibition of biofilm cell metabolic activity. The maximum leaf number influence of planting date on yield and quality characteristics of two garlic allium sativum cultivars in sicily.
Preclinical studies have shown that allicin, a major component of garlic, may affect cytochrome p 450 3a4 cyp3a4 activity. This study evaluated the neuroprotective potential of allium sativum against monosodium glutamate msginduced neurotoxicity with respect to its impact on shortterm memory in rats. Comparison of antimicrobial activity of allium sativum. Tyler skip to main content accessibility help we use cookies to distinguish you from other users and to provide you with a better experience on our websites. Allicin, the antibacterial principle of allium sativum. The present study investigates in vitro regeneration of three garlic cultivars. Article information, pdf download for protective effect of. Evaluation of fungal microflora for aflatoxin producing. This study examines the influence of garlic supplementation on the pharmacokinetics of docetaxel, a cyp3a4 substrate. Its close relatives include the onion, shallot, leek, chive, and chinese onion. Look up sativa, sativum, or sativus in wiktionary, the free dictionary sativa, sativus, and sativum are latin botanical adjectives meaning cultivated often associated botanically with plants that promote good health and used to designate certain seedgrown domestic crops. Pooled data from numerous randomized trials suggest that garlic.
Collage, vidisha and was also confirmed by standard book. Allium sativum is a suitable candidate because of its relative abundance. The herbal supplement garlic allium sativum is commonly used by cancer patients. Pdf role of garlic allium sativum in various diseases. Garlic allium sativum and onion allium cepa is widely grown and is easy to cultivate in gardens. Allium tuberosum species of garlic was found more potent p allium sativum in reducing severity of atherosclerosis. Journal of food composition and analysis 2004, 17 2, 235245. The seeds are harvested when almost mature and eaten fresh as shelled peas or the pods can be left to mature when the mature seeds are harvested and used dried. It is native to central asia and northeastern iran, and has long been a common seasoning worldwide, with a history of several thousand years of. Phytopharmacological properties of coriander sativum as a potential medicinal tree.
An overview pathak nimish l, kasture sanjay b, bhatt nayna m and rathod jaimik d abstract coriandrum sativum family umbelliferae is highly reputed ayurvedic medicinal tree commonly known as the dhanyaka. Forty male wistar albino rats were assigned into four groups. There has been a global surge in the number of diabetic cases. Proper identification of the plant was carried out by the botany department of the s. Extraction and physicochemical determination of garlic allium sativum l. B activity, the journal of nutrition, volume 3, issue 7, july 2003, pages 2171.
List of various diseases cured by lepidium sativum. Vogelbioforce uses an oil macerate made from fresh garlic cloves and rapeseed oil. Formulation and evaluation of allium sativum tablets for. A study on clinical efficacy of lepidium sativum seeds in treatment of bronchial asthma ijpt. Sensitivity of food pathogens to garlic allium sativum kumar. Inhibition of candida adhesion to buccal epithelial cells. Garlic is one of the most important bulb vegetables, which is used as spice and flavoring agent for foods garlic adds to taste of foods as well as it helps to make them digestible.
Aged garlic extract, ajo, alli sativi bulbus, allium, camphor of the poor, clove garlic, nectar of the gods, poor mans treacle, rust treacle, stinking rose12 ii. Allium cepa and garlic allium sativum as pest control. Pdf in vitro propagation of garlic allium sativum l. Pdf african journal of biotechnology ethanolic allium.
Bulbs of allium sativum plant collected from vidisha and bhopal district of madhya pradesh. Advances in food technology and nutritional sciences open journal aftnsoj. It has been considered as an important medicinal plant since the vedic era. Exploration of efficacious plant extracts that can reduce or inhibit pseudomonas aeruginosa biofilm formation is necessary. Names of lepidium sativum in various languages of the world are also given. In this study, the garlic powders were blended in ultrashear homogenizer for one min using 10 ml of. Pdf potential health benefits of garlic allium sativum. Morphological characteristics of garlic allium sativum l. Chemical composition and bioactive compounds of garlic. It has been used as a medicinal agent for thousands of years.
Pisum sativum peas are hardy annual plants native to eurasia that have been grown since 7,000 b. Indian journal of natural products and resources vol. Journal of horticulture and forestry effect of manure. Overview garlics current principal medicinal uses are to prevent and treat cardiovascular disease by lowering blood pressure and cholesterol, as an antimicrobial, and as a preventive agent for cancer. Potential health benefits of garlic allium sativum.
Extraction and physicochemical determination of garlic. Although garlic is believed to have healthpromoting benefits, many of the claimed benefits are not supported by good scientific studies. The inhibitory activity of garlic allium sativum against staphylococcus aureus, salmonella typhi, escherichia coli and listeria monocytogenes. Its medicinal use is based on traditional experience passed from generation to. Garlic allium sativum is a source of medicine in many ways in human beings in routine life as well as in animals and its leaves, flowers, and cloves have been used in traditional medicine for a long time. Scanning electron microscopy and cell leakage studies showed that garlic treatment affected the structure and integrity of the outer surface of the yeast cells. Allium sativum is cultivated all over the world in a warm, moderate climate and is used largely as a herb and a vegetable. Lepidium sativum herb uses, benefits, cures, side effects. Pdf 603 k pdf plus 284 k methiin as a nematode attractant in allium sativum. Allicin is thought to be the principal bioactive compound present in aqueous garlic extract or raw garlic homogenate. International journal of food and nutrition science vol1 no2 march 2012 4 allium abstractthe oil was extracted from powder of garlic cloves using soxhlet extraction method with nhexane as the solvent. Both varieties are composed of an underground bulb made up of cloves, which are prophylls enclosed by dry membranous skins and held together by a basal plate. Journal of complementary and integrative medicine volume 5, issue 1 2008 article 1 potential health bene.
Pdf chemical constituents and pharmacological activities of. Science and therapeutic application of allium sativum l. Antiinflammatory effect and cardiovascular effects of garlic. Please leave a message, we will get back you shortly.
Canadian journal of botany canadian science publishing. Pea belongs to the plant family leguminosae also known as fabaceae and, like many legumes, it has the ability to fix nitrogen from the air through a symbiotic relationship with bacteria housed in root nodules, making. Pdf molluscicidal activity of the aqueous extract of. Immunomodulation and antiinflammatory effects of garlic. Stereoisomers of 52allylsulfinyl3,4dimethylthiolane2ol, a family of 3,4dimethylthiolanes of formula c9h16o2s2 we name ajothiolanes, were isolated from garlic allium sativum macerates and characterized by a variety of analytical and spectroscopic techniques, including ultraperformance liquid chromatography uplc, direct analysis in real timemass spectrometry dartms, and liquid. We evaluated and compared the effects of single and combined oral administration of fresh aqueous onion allium cepa and garlic allium sativum extracts at different concentrations on some immunological determinants in rats. Modulates cytokine expression in lipopolysaccharideactivated human blood thereby inhibiting nf. Allium sativum is further divided into two subspecies, a. Lechalote ses bienfaits, ses principes actifs, ses differences avec l. Lepidium sativum is widely used in folk medicine for treatment of hyperactive airways disorders, such as asthma, bronchitis and cough. Studies on the anticandidal mode of action of allium. Although garlic has been used for its medicinal properties for thousands of years, investigations into its mode of action are relatively recent. Md shahab uddin abstract garlic allium sativum the liliaceae family, is among the oldest of all cultivated plants.
Protective effect of diallylsulphide against mercuric. Many of the agents used as antidiabetic are either expensive or have side effects. A study on clinical efficacy of lepidium sativum seeds in. Allium sativum in world checklist of selected plant families. Garlic allium sativum is a species in the onion genus, allium. Sampath kumar 1, debjit bhowmik 2, chiranjib 2, pankaj tiwari 2, rakesh kharel 2 1dept. The aim of this study was to examine the inhibition of. Cardiovascular benefits of garlic allium sativum l.
Resurgence in the use of natural herbal alternatives has brought. The oil is light yellow in colour with a pungent smell. Processed black garlic allium sativum extracts enhance anti. Researchers are now turning their attention to phytotherapy as a viable alternative in the treatment of hyperglycemia. International journal of pharmaceutical sciences and research 3528 figure 6. The vast majority of recent randomized, placebocontrolled studies do not support a role for. International journal of agriculture and biology 1.
Composition of garlic essential oil allium sativum l. Classification of genetic variation in garlic allium sativum. Noboru takada, a sayaka sutoh, a masuru toyota, a yoshihisa yamazaki, b nozomi kitanoyamashita, c chisato ushida, a kazuo yamashita c. The beneficial health effects of garlic are well documented, including its reduction of blood clotting that is observed at high concentrations berginc and kristl, 20. Methiin as a nematode attractant in allium sativum. Garlic is a strongly aromatic bulb crop that has been cultivated for thousands of years. Ferreira2 1department of agriculture crop production and rural environment, university of thessaly, fytokou str, 38446, nea ionia, magnesia, greece. Review of the health benefits of peas pisum sativum l. Article pdf available in research journal of pharmacy and.
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